Journal of Child Neurology

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here to register today!

Click here for more information

Sign In to gain access to subscriptions and/or personal tools.
This Article
Right arrow Full Text (OnlineFirst[PDF])
Right arrow Order Full text via Infotrieve
Right arrow All Versions of this Article:
0883073807309241v1
23/4/455    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrow Add to My Marked Citations
Google Scholar
Right arrow Articles by Micklewright, J. L.
Right arrow Articles by Krawiecki, N.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Micklewright, J. L.
Right arrow Articles by Krawiecki, N.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
First published on January 8, 2008, doi:10.1177/0883073807309241

Journal of Child Neurology 2008;23:455.

A more recent version of this article appeared on April 1, 2008
 © 2008 SAGE Publications

Article

Quantifying Pediatric Neuro-oncology Risk Factors: Development of the Neurological Predictor Scale

Jackie L. Micklewright, MA1, Tricia Z. King, PhD1*, Robin D. Morris, PhD1, and Nicolas Krawiecki, MD2

1 Georgia State University, Atlanta, Georgia
2 Emory University School of Medicine, Atlanta, Georgia

* To whom correspondence should be addressed. E-mail: tzking{at}gsu.edu.


  Abstract
Pediatric neuro-oncology researchers face methodological challenges associated with quantifying the influence of tumor and treatment-related risk factors on child outcomes. The Neurological Predictor Scale was developed to serve as a cumulative index of a child’s exposure to risk factors. The clinical utility of the Neurological Predictor Scale was explored in a sample of 25 children with heterogeneous brain tumors. Consistent with expectation, a series of regression analyses demonstrated that the Neurological Predictor Scale significantly predicted composite intellectual functioning (r2 = 0.21, p < .05), short-term memory (r2 = 0.16, p = .05), and abstract visual reasoning abilities (r2 = 0.28, p < .05). With the exception of chemotherapy, the Neurological Predictor Scale accounted for a significant amount of the variance in child intellectual functioning above and beyond individually examined variables. The Neurological Predictor Scale can be used to quickly quantify the cumulative risk factors associated with pediatric brain tumor diagnoses.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?