Journal of Child Neurology

 

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First published on May 16, 2008
Journal of Child Neurology 2008, doi:10.1177/0883073808315420


Article

Severe Ataxia as a Complication of Human Parvovirus B19 Acute Encephalitis in a Child

Filippo Greco, MD*, Maria Luisa Barbagallo, MD, Danilo Castellano Chiodo, MD, Rosanna Guglielmino, MD, and Giovanni Sorge, MD

Department of Pediatrics, University of Catania, Catania, Italy

* To whom correspondence should be addressed. E-mail: coicoico{at}hotmail.com.


   Abstract
Human parvovirus B19 generally causes erythema infectiosum in childhood, but it can be associated with unusual findings, particularly in immunocompromised patients. This is a report about an immunocompetent 4-year-old female child affected with acute encephalitis by parvovirus B19, documented by polymerase chain reaction performed on cerebrospinal fluid, who was treated with intravenous immunoglobulins and dexamethasone and who developed a cerebellar syndrome with ataxia, dysmetria, and dysarthria. To the best of the authors’ knowledge, this may be the first report of human parvovirus B19 encephalitis complicated by severe ataxia in childhood.


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