Journal of Child Neurology

 

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First published on April 10, 2008, doi:10.1177/0883073808315443

Journal of Child Neurology 2008;23:948.

A more recent version of this article appeared on August 1, 2008

Article

An Unusual Manifestation of a Neonatal Chlamydia Infection

Astrid Bertsche, MD1*, Mathias H. Wagner, MD1, Renate Bollmann, PhD2, Michael Obladen, PhD1, and Ursula Felderhoff-Mueser, PhD1

1 Department of Neonatology Campus Virchow-Klinikum, Charité Universitätsmedizin, Berlin, Germany
2 Department of Microbiology and Hygiene, Charité Universitätsmedizin, Berlin, Germany

* To whom correspondence should be addressed. E-mail: astrid.bertsche{at}med.uni-heidelberg.de.


  Abstract
A 25-day-old boy was admitted to hospital because of pneumonia and additionally developed symptoms of encephalitis. The immune fluorescence test for Chlamydia trachomatis in tracheal fluids was positive. Furthermore, ligase chain reaction for C trachomatis was positive in the cerebrospinal fluid. The antibiotic regimen was changed to erythromycin intravenously. C trachomatis encephalitis is rare in neonates and may result from a defect in the alternative pathway of complement activation which was the case in this patient.


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