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Journal of Child Neurology
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Article

Successful Treatment With Sumatriptan in a Case With Cyclic Vomiting Syndrome Combined With 18q– Syndrome

Yosuke Kakisaka, MD1*, Keisuke Wakusawa, MD1, Ikuko Sato, MD1, Kazuhiro Haginoya, MD1, Mitsugu Uematsu, MD1, Mieko Hirose, MD1, Mitsutoshi Munakata, MD1, Tetsuo Sato, MD2, and Shigeru Tsuchiya, MD1

1 Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan
2 Kesennuma City Hospital, Kesennuma, Japan

* To whom correspondence should be addressed. E-mail: kakisuke{at}mui.biglobe.ne.jp.


   Abstract

The authors present a 14-year-old girl with 18q– syndrome combined with cyclic vomiting syndrome. Since the age of 5 years, she has been admitted to hospital 30 times. Despite trying many prophylactic treatments, no medication has inhibited the vomiting attacks successfully. Intranasal sumatriptan was effective at halting the vomiting attacks. This is the first case of 18q– syndrome combined with cyclic vomiting syndrome successfully treated with sumatriptan. This report may allow us to consider sumatriptan use in patients suffering from misery attack of cyclic vomiting syndrome combined with chromosomal abnormality of 18q– syndrome.

First published on September 30, 2009
Journal of Child Neurology 2009, doi:10.1177/0883073809334384


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