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Journal of Child Neurology
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Midline Telencephalic Dysgenesis: Report of Three Cases

Richard W. Leech, MD

Department of Pathology, University of Oklahoma College of Medicine, Oklahoma City, OK

Robert M. Shuman, MD

Department of Pathology, University of Oklahoma College of Medicine, Oklahoma City, OK

A series of three complex cerebral malformations is presented. The series was characterized by incomplete development of the commissural and chiasmatic plate of the developing forebrain. Associated anomalies included hypoplasia of the hippocampus, heterotopias, and nonfusion of the cerebellum. Mild facial anomalies were present, as were somatic anomalies of the heart and kidneys. Emphasis is placed on the order and classification of similar cerebral anomalies. (J Child Neurol 1986;1:224-232)

Journal of Child Neurology, Vol. 1, No. 3, 224-232 (1986)
DOI: 10.1177/088307388600100309
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Home page
 Arch NeurolHome page
C. L. Coulter, R. W. Leech, G. B. Schaefer, B. W. Scheithauer, and R. A. Brumback
Midline Cerebral Dysgenesis, Dysfunction of the Hypothalamic-Pituitary Axis, and Fetal Alcohol Effects
Arch Neurol, July 1, 1993; 50(7): 771 - 775.
[Abstract] [PDF]