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Journal of Child Neurology
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*Compound via MeSH
*Substance via MeSH
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*Bipolar Disorder
Hazardous Substances DB
*LITHIUM CARBONATE
*LITHIUM COMPOUNDS
*LITHIUM, ELEMENTAL
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Manic-Depressive Illness in Children: Treatment With Lithium Carbonate

Robert P. Younes, MD

Department of Pediatrics, Carney Hospital, Boston

G. Robert DeLong, MD

the Pediatric Neurology Unit, Massachusetts General Hospital, Boston

George Neiman, MA

Massachusetts General Hospital

Bernard Rosner, PhD

Department of Statistics, Harvard University, Cambridge, MA

A behavior questionnaire was used retrospectively in 21 manic-depressive children to quantitate manic-depressive behaviors before and after treatment with lithium carbonate. The study children were matched with 21 control children for age, race, sex, and socioeconomic status. The study children had significantly more seizures, relatives with psychotic disorders, allergies, food sensitivities, headaches, and abnormal behaviors in all categories measured. During treatment, manic-depressive children had a statistically significant reduction in disturbed behavior. This behavior, however, was still significantly more disturbed than normal control children. (J Child Neurol 1986;1:364-368)

Journal of Child Neurology, Vol. 1, No. 4, 364-368 (1986)
DOI: 10.1177/088307388600100409
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