This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Brook, I. Search for Related Content PubMed PubMed Citation Articles by Brook, I. Social Bookmarking                         What's this?

Topical Review: Brain Abscess in Children: Microbiology and Management

Department of Pediatrics, Georgetown University School of Medicine, Washington, DC

Brain abscess is a serious, life-threatening infection. The infection can originate from contiguous sites of existing infections, such as chronic otitis media, dental infection, mastoiditis, or sinusitis, where anaerobic bacteria predominate. The infection can also occur in children with cyanotic congenital heart disease, in whom the predominant organisms are viridans, microaerophilic, or anaerobic streptococci, or after head trauma, in which case Staphylococcus aureus, viridans cocci, and Streptococcus pneumoniae are the most prevalent isolates. Enterobacteriaceae, Pseudomonas aeruginosa, yeast, fungi, and mycobacteria are prevalent in the immunocompromised. Radioisotope brain scans, computed tomography, and magnetic resonance imaging are important tools that enable accurate diagnosis of the infection. Proper selection of antimicrobial with good intracranial penetration is essential in the management of intracranial infection. Delay in surgical drainage can be associated with high mortality or morbidity. However, brain abscess, especially in the early phase of cerebritis, may respond to antimicrobial therapy without surgical drainage. (J Child Neurol 1995;10:283-288).

Journal of Child Neurology, Vol. 10, No. 4, 283-288 (1995)
DOI: 10.1177/088307389501000405


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				H. P. Goodkin, M. B. Harper, and S. L. Pomeroy Intracerebral Abscess in Children: Historical Trends at Children's Hospital Boston Pediatrics, June 1, 2004; 113(6): 1765 - 1770. [Abstract] [Full Text] [PDF]

				D. A. Hill, G. Gridley, S. Cnattingius, L. Mellemkjaer, M. Linet, H.-O. Adami, J. H. Olsen, O. Nyren, and J. F. Fraumeni Jr Mortality and Cancer Incidence Among Individuals With Down Syndrome Arch Intern Med, March 24, 2003; 163(6): 705 - 711. [Abstract] [Full Text] [PDF]