Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more information

CiteULike is a free service for managing and discovering scholarly references - click here to get started.

Sign In to gain access to subscriptions and/or personal tools.
Journal of Child Neurology
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Brill, C. B.
Right arrow Articles by Mishkin, M. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Brill, C. B.
Right arrow Articles by Mishkin, M. M.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Chiari I Malformation: Association With Seizures and Developmental Disabilities

Charles B. Brill, MD

Departments of Pediatrics and Neurology, Thomas Jefferson University Hospital, Philadelphia, PA

Juan Gutierrez, MD

Department of Radiology Thomas Jefferson University Hospital, Philadelphia, PA

Mark M. Mishkin, MD

Department of Radiology Thomas Jefferson University Hospital, Philadelphia, PA

Chiari I malformation, a congenital abnormality in which deformed cerebellar tonsils are displaced downward through the foramen magnum, commonly presents in patients with headache or symptoms of dysfunction of the cerebellum, brain stem, and cervical spinal cord. We report 11 children with Chiari I malformation who presented with seizures and developmental delay in motor or language function with or without autistic features. To our knowledge, an association between Chiari I malformation and seizures or neurodevelopmental deficits or both has not been previously reported. We believe that Chiari I malformation should not be considered an incidental finding in these patients, but may be a marker for subtle cerebral dysgenesis. Chiari I and II malformations may constitute a complex but continuous spectrum, related to the timing and severity of a shared underlying embryologic mechanism. (J Child Neurol 1997;12:101-106).

Journal of Child Neurology, Vol. 12, No. 2, 101-106 (1997)
DOI: 10.1177/088307389701200206
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Anesth. Analg.Home page
R. Landau, R. Giraud, V. Delrue, and C. Kern
Spinal Anesthesia for Cesarean Delivery in a Woman with a Surgically Corrected Type I Arnold Chiari Malformation
Anesth. Analg., July 1, 2003; 97(1): 253 - 255.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
Y. W. Wu, C. T. Chin, K. M. Chan, A. J. Barkovich, and D. M. Ferriero
Pediatric Chiari I malformations: Do clinical and radiologic features correlate?
Neurology, October 1, 1999; 53(6): 1271 - 1271.
[Abstract] [Full Text]

Home page
 J Child NeurolHome page
M. Elia, R. Biondi, V. Sofia, S. A. Musumeci, R. Ferri, G. Capovilla, and P. Curatolo
Seizures in Chiari I Malformation: A Clinical and Electroencephalographic Study
J Child Neurol, July 1, 1999; 14(7): 446 - 450.
[Abstract] [PDF]

Home page
 J Child NeurolHome page
A. Parmeggiani, A. Posar, M. C. Scaduto, S. Chiodo, M. Santucci, and P. Giovanardi Rossi
Posterior Fossa Malformations and Epilepsy
J Child Neurol, February 1, 1999; 14(2): 113 - 117.
[Abstract] [PDF]