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Chronic Meningoencephalitis due to Cytomegalovirus Infection in a Nonimmunocompromised Patient: An Autopsy Case

Department of Neurology

Junko Shiobara, MD

Department of Neurology

Yuji Iwasaki, MD

Department of Neurology

Yoshifumi Ogiso, MD

Department of Clinical Pathology Nagano Children's Hospital 3100 Toyoshima Nagano 399-8288, Japan

Noriko Kubota, BS

Department of Clinical Pathology Nagano Children's Hospital 3100 Toyoshima Nagano 399-8288, Japan

Akira Oka, MD

Department of Mental Retardation and Birth Defect Research National Institute of Neuroscience National Center of Neurology and Psychiatry Kodaira, Tokyo, Japan

Sachio Takashima, MD

Department of Mental Retardation and Birth Defect Research National Institute of Neuroscience National Center of Neurology and Psychiatry Kodaira, Tokyo, Japan

Congenital cytomegalovirus infection, which is the most common of the intrauterine viral infections, is well known to involve various organs, including the central nervous system. On the other hand, encephalitis due to persistent or acquired infection by cytomegalovirus in the central nervous system is thought to be rare, and to be seen exclusively in immunocompromised patients such as those under immunosuppressant therapy or those with acquired immunodeficiency syndrome (AIDS). We describe chronic meningoencephalitis possibly due to cytomegalovirus seen in an immunocompetent patient with behavior problems.

Journal of Child Neurology, Vol. 13, No. 11, 570-573 (1998)
DOI: 10.1177/088307389801301108


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