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Journal of Child Neurology
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Children Who Can't Smell the Coffee: Isolated Congenital Anosmia

Sarit Assouline, MD, CM

Divisions of Pediatric Neurology Montreal Children's Hospital, Department of Human Genetics McGill University, Montreal, Quebec, Canada

Michael I. Shevell, MD, CM, FRCPC

Divisions of Pediatric Neurology Montreal Children's Hospital, Department of Pediatrics and Neurology/Neurosurgery McGill University, Montreal, Quebec, Canda, Department of Human Genetics McGill University, Montreal, Quebec, Canada

Robert J. Zatorre, PhD

Division of Neuropsychology/Cognitive Neurosciences Unit Montreal Neurological Institute, Department of Psychology McGill University, Montreal, Quebec, Canada

Marilyn Jones-Gotman, PhD

Division of Neuropsychology/Cognitive Neurosciences Unit Montreal Neurological Institute, Department of Psychology McGill University, Montreal, Quebec, Canada

Melvin D. Schloss, MD, FRCSC

Division of Otolaryngology Montreal Children's Hospital, Department of Otolaryngology McGill University, Montreal, Quebec, Canada

Kalmadine Oudjhane, MD

Division of Medical Imaging Montreal Children's Hospital, Department of Radiology McGill University, Montreal, Quebec, Canada

Two children with isolated congenital anosmia, a rare syndrome of deficient restricted neuronal migration, are presented with early diagnosis confirmed by standardized smell testing and detailed neuroimaging studies. Recognition of this disorder and its spectrum of presentations provides important insights into the molecular mechanisms underlying the development of the olfactory system. (J Child Neurol 1998;13:168-172).

Journal of Child Neurology, Vol. 13, No. 4, 168-172 (1998)
DOI: 10.1177/088307389801300404
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