This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Ozawa, H. Articles by Kaga, M. Search for Related Content PubMed PubMed Citation Articles by Ozawa, H. Articles by Kaga, M. Social Bookmarking                         What's this?

Somatosensory Evoked Potentials With a Unilateral Migration Disorder of the Cerebrum

Department of Child Neurology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry (NCNP), Kodaira, Tokyo, Japan

Masumi Inagaki, MD

Department of Developmental Disorders National Institute of Mental Health, NCNP, Ichikawa, Chiba, Japan

Hiroshi Aikoh, MD

Department of Child Neurology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry (NCNP), Kodaira, Tokyo, Japan

Shigeru Hanaoka, MD

Department of Child Neurology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry (NCNP), Kodaira, Tokyo, Japan

Kenji Sugai, MD

Department of Child Neurology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry (NCNP), Kodaira, Tokyo, Japan

Toshiaki Hashimoto, MD

Department of Child Neurology, National Center Hospital for Mental, Nervous, and Muscular Disorders, National Center of Neurology and Psychiatry (NCNP), Kodaira, Tokyo, Japan

Makiko Kaga, MD

Department of Developmental Disorders National Institute of Mental Health, NCNP, Ichikawa, Chiba, Japan

The somatosensory evoked potentials in two children with a unilateral migration disorder (pachygyria) of the cerebrum, which was detected by MRI, were examined in order to evaluate the function of the malformed sensory cortex. A 5-year-old girl had slight left hemiparesis, seizures, and mental retardation, and a 4-month-old boy had left hemiparesis. Neither patient showed distinct sensory disturbance. Short latency somatosensory evoked potentials and somatosensory evoked potentials recordings demonstrated that the early cortical component, N20, was absent and a positive wave appeared on paretic left-hand stimulation. On nonparetic right-hand stimulation, the primary evoked response (N20-P30) of the left hemisphere, which originates in Broadmann area 3b, was almost normal. Multichannel recordings on the scalp of one patient revealed that a positive wave without polarity inversion appeared posterior to the right central sulcus on median nerve stimulation on the paretic side. The radial dipole in the sensory cortex (area 1 or area 3a) or motor cortex (area 4) could have formed the positive/negative biphasic wave in the relatively wide centroparietal area in the present patients. In the case of unilateral cortical dysplasia, the malformed cortex with subnormal function of sensation might induce the change in the early component of somatosensory evoked potentials. (J Child Neurol 1998;13:211-215).

Journal of Child Neurology, Vol. 13, No. 5, 211-215 (1998)
DOI: 10.1177/088307389801300503


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				T. Akai, H. Otsubo, E. W. Pang, J. T. Rutka, S. Chitoku, S. K. Weiss, and O. C. Snead Complex Central Cortex in Pediatric Patients With Malformations of Cortical Development J Child Neurol, May 1, 2002; 17(5): 347 - 352. [Abstract] [PDF]