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Topical Review: Pathologic Basis of the Symptomatic Epilepsies in Childhood

Departments of Pathology and Pediatrics and the Section of Neurophysiology, Baylor College of Medicine, Houston, TX

Eli M. Mizrahi, MD

Department of Neurology and Section of Pediatric Neurology, Baylor College of Medicine, Houston, TX, Department of Pediatrics Baylor College of Medicine, Houston, TX

The epilepsies in childhood are classified as primary (or idiopathic) and secondary (or symptomatic). The primary epilepsies account for two thirds of all childhood epilepsies and are presumed to be genetically determined. In the remaining one third of cases, a neuropathologic lesion can be identified. This paper summarizes the etiologies of the symptomatic epilepsies. They are classified according to the pathologic processes; malformative, metabolic, neoplastic and phakomatoses, hypoxic-ischemic, infectious, and of unknown pathologic process. (J Child Neurol 1998;13:361-371).

Journal of Child Neurology, Vol. 13, No. 8, 361-371 (1998)
DOI: 10.1177/088307389801300801


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