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Phenytoin-Associated Thrombocytopenia in a Toddler

Division of Child Neurology

Edward C. Russell, MD

Division of Pediatric Hematology- Oncology

John M. Pellock, MD

Division of Child Neurology Medical College of Virginia of Virginia Commonwealth University Richmond, VA, jpellock{at}gems.vcu.edu

Hematologic side effects are rare side effects of treatment with phenytoin. We report a 2-year-old girl who developed reversible thrombocytopenia following treatment with phenytoin. Thrombocytopenia as a side effect of phenytoin treatment has usually been reported in adults and generally occurs 2 to 4 weeks after initiation of therapy. In our case, the thrombocytopenia developed on the 11th day of therapy and resolved 5 days after discontinuation of the phenytoin. (J Child Neurol 1999;14:130-131).

Journal of Child Neurology, Vol. 14, No. 2, 130-131 (1999)
DOI: 10.1177/088307389901400212


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