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Journal of Child Neurology
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Topical Review: Management of the Respiratory Complications of Neuromuscular Diseases in the Pediatric Intensive Care Unit

David J. Birnkrant, MD

Department of Pediatrics, Case Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, OH

John F. Pope, MD

Department of Pediatrics, Case Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, OH

Robert M. Eiben, MD

Children's Hospital Medical Center, Akron, OH

Pediatric neuromuscular diseases such as Duchenne muscular dystrophy and spinal muscular atrophy cause pulmonary compromise. In severely affected patients, upper respiratory tract infections exacerbate lower respiratory tract secretion retention, with the potential for pneumonia, pulmonary atelectasis, and respiratory failure. In the pediatric intensive care unit, effective treatment includes noninvasive positive pressure ventilation and manual and mechanical mucus clearance techniques. A practical approach to commonly encountered respiratory complications in pediatric neuromuscular diseases is presented in this review. (J Child Neurol 1999; 14:139-143).

Journal of Child Neurology, Vol. 14, No. 3, 139-143 (1999)
DOI: 10.1177/088307389901400301
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