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Journal of Child Neurology
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Plasma Baclofen Levels in Children Receiving Continuous Intrathecal Baclofen Infusion

A. Leland Albright

Department of Neurosurgery Children's Hospital of Pittsburgh Pittsburgh, Pennsylvania

Barbara L. Shultz

Department of Neurosurgery Children's Hospital of Pittsburgh Pittsburgh, Pennsylvania

To determine the plasma baclofen concentrations of children undergoing continuous intrathecal baclofen infusion for treatment of cerebral spasticity, we assayed plasma samples from six children, 8 to 18 years of age, who were receiving intrathecal baclofen at constant rates of 77 to 400 µg/day. Plasma levels were at or below the limit of quantification (10 ng/mL) in all patients. (J Child Neurol 1999;14:408-409).

Journal of Child Neurology, Vol. 14, No. 6, 408-409 (1999)
DOI: 10.1177/088307389901400611
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