This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Pena, J. A. Articles by Cardozo, J. Search for Related Content PubMed PubMed Citation Articles by Pena, J. A. Articles by Cardozo, J. Social Bookmarking                         What's this?

Hallervorden-spatz Disease: Two New Early Childhood Onset Cases

Department of Pediatric Neurology, School of Medicine, University of Zulia, Maracaibo, Venezuela, jokarl{at}telcel.net.ve

Omaira Molina, MD

Department of Neurology, University of Zulia, Maracaibo, Venezuela

Jose Cardozo, MD

Department of Neuroanatomy School of Medicine, University of Zulia, Maracaibo, Venezuela

Hallervorden-Spatz disease is a rare, autosomal-recessive hereditary condition characterized by early onset of progressive movement alterations such as dystonia, rigidity, and choreoathetosis, which is usually associated with pyramidal signs and mental deterioration. The authors report two cases for which diagnosis of Hallervorden-Spatz disease was based on clinical manifestations that appeared during the first year of life, illness progression, and late-stage magnetic resonance imaging findings. The possibility that these two cases, along with other previously described rare instances with similar clinical features, be considered as a variant of subtype of the early-onset type of Hallervorden-Spatz disease is suggested. The need to differentiate these cases from cases of static encephalopathy with mental retardation and motor impairment is also stressed. (J Child Neurol 2000;15:30-32).

Journal of Child Neurology, Vol. 15, No. 1, 30-32 (2000)
DOI: 10.1177/088307380001500107


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?