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Journal of Child Neurology
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Usefulness of Diagnostic Criteria of Tuberous Sclerosis Complex in Pediatric Patients

Sergiusz Józwiak, MD, PhD

Department of Pediatric Neurology, Children's Memorial Hospital, Warsaw, Poland

Robert A. Schwartz, MD, MPH

Departments of Dermatology and Pediatrics, New Jersey Medical School, Newark, NJ

Camila Krysicka Janniger, MD

Departments of Dermatology and Pediatrics, New Jersey Medical School, Newark, NJ

Jolanta Bielicka-Cymerman, MD, PhD

Department of Pediatric Neurology, District Hospital, Warsaw, Poland

The Tuberous Sclerosis Complex 1998 Consensus Conference clinical criteria represent an important advance in the diagnosis of tuberous sclerosis complex. Since many findings regarded as highly specific for tuberous sclerosis complex are not apparent until late childhood or adulthood, refinements by age may prove of value. We have stratified 106 children into five age groups (0 to 2 years of age, above 2 to 5 years, above 5 to 9 years, above 9 to 14 years, and above 14 to 18 years). Physicians should be alerted as to the frequency of the criteria in different stages of children. (J Child Neurol 2000;15:652-659).

Journal of Child Neurology, Vol. 15, No. 10, 652-659 (2000)
DOI: 10.1177/088307380001501003
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