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Journal of Child Neurology, Vol. 16, No. 10, 762-763 (2001)
DOI: 10.1177/088307380101601010

Possible Role of High-Dose Corticosteroids in the Treatment of Cat-Scratch Disease Encephalopathy

Koren D. Weston, MD

Division of Pediatric Neurology Department of Pediatrics University of Florida College of Medicine Gainesville, Florida

Thang Tran, BS

Division of Pediatric Neurology Department of Pediatrics University of Florida College of Medicine Gainesville, Florida

Kimberly N. Kimmel, BS

Division of Pediatric Neurology Department of Pediatrics University of Florida College of Medicine Gainesville, Florida

Bernard L. Maria, MD, MBA

Division of Pediatric Neurology Department of Pediatrics University of Florida College of Medicine Gainesville, Florida

Approximately 2% of the estimated 24,000 patients in the United States who contract cat-scratch disease annually develop neurologic complications. Between 1989 and 1999, 36 patients were admitted to our hospital with cat-scratch disease; 25% had neurolugic complications, and the majority experienced lengthy hospital stays. We describe a case of cat-scratch disease encephalopathy in a 4-year-old girl who responded to high-dose corticosteroid therapy. Further studies are warranted to determine if corticosteroid therapy shortens the duration of symptoms, lessens the severity of disease, and ultimately improves the outcome for patients with cat-scratch disease encephalopathy. (J Child Neurol 2001;16:762-763).


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