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Journal of Child Neurology
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Reviews

Topical Review: Long-Term Developmental Outcome of Asphyxiated Term Neonates

Marie-Emmanuelle Dilenge, MD, FRCP

Division of Pediatric Neurology, Montreal Children's Hospital, McGill University, Montreal, PQ, dilenge{at}bic.mni.mcgill.ca

Annette Majnemer, PhD

Division of Pediatric Neurology, Montreal Children's Hospital, McGill University, Montreal, PQ, School of Physical and Occupational Therapy, McGill University, Montreal, PQ, Department of Neurology/ Neurosurgery and Pediatrics, McGill University, Montreal, PQ

Michael I. Shevell, MDCM, FRCP

Division of Pediatric Neurology, Montreal Children's Hospital, McGill University, Montreal, PQ, Department of Neurology/ Neurosurgery and Pediatrics, McGill University, Montreal, PQ

Asphyxia remains one of the main causes of later disability in term infants. Despite many publications identifying possible predictors of outcome in this population of interest, little is known of the long-term developmental outcome of asphyxiated term neonates. Observational studies have largely focused on short-term outcomes, with an emphasis on significant neurologic sequelae and intellectual impairments. This article reviews the literature that has described the developmental outcome of asphyxiated term newborns. As part of this review, we have also highlighted the evolution of the definition of asphyxia and delineated appropriate markers that should be used in future research on this population. (J Child Neurol 2001;16:781—792).

Journal of Child Neurology, Vol. 16, No. 11, 781-792 (2001)
DOI: 10.1177/08830738010160110201


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