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Journal of Child Neurology
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Enteroviral Encephalitis Leading to a Locked-in State

Victoria Z. Acharya, MD

Department of Pediatrics, Phoenix Children's Hospital, Phoenix, Arizona

Dinesh Talwar, MD

Pediatric Neurologic Associates, University of Arizona College of Medicine Tucson, Arizona

Sean P. Elliott, MD

Department of Pediatrics, Section of Infectious Diseases, University of Arizona College of Medicine Tucson, Arizona, selliott{at}peds.arizona.edu.

Millions of children are infected by enteroviruses each year, usually exhibiting only mild symptoms. Although enteroviruses are a common cause of community-acquired aseptic meningitis, enteroviral meningitis usually has a benign course. We describe a 14-year-old patient with enteroviral meningoencephalitis diagnosed by polymerase chain reaction. Her level of consciousness declined rapidly after hospital admission and resulted in a locked-in state. Although she experienced slow neurologic improvement, residual neurologic deficits remain. Although there is a general awareness of the characteristics of enteroviral encephalitis, this case report is significant in presenting a case of unusual severity and sequelae. To our knowledge, this is the first published report of an enterovirus encephalitis leading to a locked-in-state. (J Child Neurol 2001;16:864—866).

Journal of Child Neurology, Vol. 16, No. 11, 864-866 (2001)
DOI: 10.1177/08830738010160111403
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