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Journal of Child Neurology
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Melatonin Replacement Therapy in a Child With a Pineal Tumor

James E. Jan, MD, FRCPC

Division of Developmental Paediatrics, Department of Paediatrics University of British Columbia Vancouver, British Columbia

Joseph Tai, PhD

Centre for Complementary Medicine Research

George Hahn, MD, FRCPC

Divisions of Developmental Paediatrics and Physical Medicine Rehabilitation

Ralph R. Rothstein, MD, FRCPC

Division of Developmental Paediatrics, Department of Paediatrics University of British Columbia Vancouver, British Columbia

The case report of a child with the diagnosis of a pineal tumor and severe, chronic sleep disorder is reported. Due to treatment of her lesion, the nighttime melatonin secretion was markedly suppressed. For 41/2 years, she has been receiving oral melatonin, which has greatly improved her sleep, without any adverse effects. Sleep difficulties should be considered in the management of pineal lesions. Melatonin replacement therapy is beneficial for those patients who have deficient melatonin synthesis. (J Child Neurol 2001;16:139-140).

Journal of Child Neurology, Vol. 16, No. 2, 139-140 (2001)
DOI: 10.1177/088307380101600215
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