This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Otsubo, H. Articles by Snead, O. C. Search for Related Content PubMed PubMed Citation Articles by Otsubo, H. Articles by Snead, O. C. Social Bookmarking                   What's this?

Topical Review: Magnetoencephalography and Magnetic Source Imaging in Children

Division of Neurology, The Hospital for Sick Children, Department of Pediatrics and the Bloorview Epilepsy Research Program, Faculty of Medicine, University of Toronto, Toronto, ON, Canada

O. Carter Snead, MD

Division of Neurology, The Hospital for Sick Children, Department of Pediatrics and the Bloorview Epilepsy Research Program, Faculty of Medicine, University of Toronto, Toronto, ON, Canada

Magnetoencephalography is a technique that detects the magnetic fields associated with the intracellular current flow within neurons, unlike electroencephalography, which measures extracellular volume currents. Superconducting quantum interference devices are used to amplify these very small magnetic field signals. Magnetic source imaging is the combination of functional data derived from magnetoencephalographic recordings coregistered with structural magnetic resonance imaging (MRI). The utility of magnetic source imaging lies in the combination of the submillisecond temporal resolution of magnetoencephalography with the precise anatomic images provided by magnetic resonance imaging. As such, magnetic source imaging is a useful tool for noninvasive localization of the epileptogenic zone in children who are candidates for epilepsy surgery. Similarly, using magnetoencephalographic recordings with evoked and event-related potentials, magnetic source imaging holds great promise as a noninvasive method for precise localization of somatosensory, motor, language, visual, and auditory cortex. Finally, magnetic source imaging is proving a valuable research tool in the investigation of epilepsy, head trauma, brain plasticity, and disorders of language, memory, cognition, and executive function in children. (J Child Neurol 2001;16:227-235).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				T. Kagan-Kushnir, S. W. Roberts, and O. C. Snead Screening Electroencephalograms in Autism Spectrum Disorders: Evidence-Based Guideline J Child Neurol, March 1, 2005; 20(3): 197 - 206. [Abstract] [PDF]