Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Click here for more information

Click here to sign up for SAGE Journal Email Alerts today!

Sign In to gain access to subscriptions and/or personal tools.
Journal of Child Neurology
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Gross-Tsur, V.
Right arrow Articles by Shalev, R. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gross-Tsur, V.
Right arrow Articles by Shalev, R. S.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Cognition, Attention, and Behavior in Prader-Willi Syndrome

Varda Gross-Tsur, MD

Neuropediatric Unit Shaare Zedek Medical Center Jerusalem, Israel

Yael E. Landau, MA

Neuropediatric Unit Shaare Zedek Medical Center Jerusalem, Israel

Fortu Benarroch, MD

Neuropediatric Unit Shaare Zedek Medical Center Jerusalem, Israel

Raaya Wertman-Elad, MA

Neuropediatric Unit Shaare Zedek Medical Center Jerusalem, Israel

Ruth S. Shalev, MD

Neuropediatric Unit Shaare Zedek Medical Center Jerusalem, Israel

We studied the academic, cognitive, and behavior profile of 18 patients with Prader-Willi syndrome. All had severe learning disabilities in arithmetic and writing, and the majority were also dyslexic. Their average Full-Scale IQ was 73.7 ± 8.9, which was 1 SD below normal range, whereas their performance on executive, memory, and visuospatial tasks ranged from 2.1 to 7.0 SD below the expected means. Behavioral problems were measured using the Child Behavior Checklist, on which the majority scored in the pathologic range for social and attention problems, delinquent and aggressive behavior, somatic complaints, and thought problems. Genotypes of the children did not predict cognitive or behavioral profile, nor could behavior be associated with parameters of weight or IQ. In summary, we found that patients with Prader-Willi syndrome have profound learning disabilities and cognitive deficits, greater than expected for their IQ. Behavioral problems, including attention-deficit hyperactivity disorder (ADHD), are also prevalent and impede the overall management of this group of patients. The genotypes were not helpful in predicting cognitive or behavioral patterns. (J Child Neurol 2001;16:288-290).

Journal of Child Neurology, Vol. 16, No. 4, 288-290 (2001)
DOI: 10.1177/088307380101600411
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 JNMHome page
S. E. Kim, D.-K. Jin, S. S. Cho, J.-H. Kim, S. D. Hong, K. H. Paik, Y. J. Oh, A. H. Kim, E. K. Kwon, and Y. H. Choe
Regional Cerebral Glucose Metabolic Abnormality in Prader-Willi Syndrome: A 18F-FDG PET Study Under Sedation
J. Nucl. Med., July 1, 2006; 47(7): 1088 - 1092.
[Abstract] [Full Text] [PDF]