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Idiopathic "Benign" Intracranial Hypertension: Case Series and Review

Division of Neurology The Hospital for Sick Children, Toronto, ON

Fenella J. Kirkham, MRCP

Great Ormond Street Hospital for Children, NHS Trust/The Neurosciences Unit Institute of Child Health, London, UK

Daune L. MacGregor, MD, FRCPC

Division of Neurology The Hospital for Sick Children, Toronto, ON

Idiopathic "benign" intracranial hypertension is an uncommon but important cause of headache that can lead to visual loss. This study was undertaken to review our experience in the diagnosis and management of idiopathic intracranial hypertension, giving special attention to treatments used. A retrospective chart review was conducted on 32 patients diagnosed with idiopathic intracranial hypertension between 1984 and 1995. Subjects included 23 females and ranged in age from 2 to 17.5 years. Headache was the most common symptom, followed by nausea and vomiting, double vision, and visual loss. Papilledema was the most common sign. Others were VIth cranial nerve palsy and compromised visual acuity at or within 3 months of presentation. Management included administration of acetazolamide or corticosteroids, lumboperitoneal shunt, optic nerve fenestration, and repeat lumbar puncture. Treatment combinations were used in 40% of cases. During follow-up, headache, papilledema, and decreased visual acuity persisted for longer than 10 months in a significant number of patients. We conclude that idiopathic intracranial hypertension causes significant short- and long-term morbidity with no proven effective treatment available. A prospective study is needed to establish the indications for treatment and the efficacy of the treatments used. (J Child Neurol 2001;16:465-470).

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				S. G. Weig Asymptomatic Idiopathic Intracranial Hypertension in Young Children J Child Neurol, March 1, 2002; 17(3): 239 - 241. [Abstract] [PDF]