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Journal of Child Neurology
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Optic Neuritis: A Novel Presentation of Schilder's Disease

Adel K. Afifi, MD

Departments of Pediatrics, Neurology and Anatomy and Cell Biology,

Kenneth A. Follett, MD

Department of Surgery (Neurosurgery)

Jeremy Greenlee, MD

Department of Surgery (Neurosurgery)

William E. Scott, MD

Department of Ophthalmology

Steven A. Moore, PhD, MD

Department of Pathology University of Iowa Hospitals and Clinics Iowa City, Iowa

The clinical features of a 7-year-old girl who presented with unilateral optic neuritis are presented. Magnetic resonance imaging (MRI) showed lesions in the affected optic nerve and the centrum semiovale bilaterally. Biopsy of one of the cerebral lesions was consistent with a diagnosis of Schilder's disease. Visual acuity returned to normal, and the demyelinating MRI lesions improved markedly with corticosteroid treatment. Optic neuritis is a novel mode of presentation in Schilder's disease. (J Child Neurol 2001;16:693-696).

Journal of Child Neurology, Vol. 16, No. 9, 693-696 (2001)
DOI: 10.1177/088307380101600915
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