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Hypomagnesemic Seizures: Case Report and Presumed PathophysiologyDivision of Child Neurology Children's Health Center and Barrow Neurological Institute St. Joseph's Hospital and Medical Center Phoenix, Arizona
Division of Child Neurology Children's Health Center and Barrow Neurological Institute St. Joseph's Hospital and Medical Center Phoenix, Arizona
Division of Child Neurology Children's Health Center and Barrow Neurological Institute St. Joseph's Hospital and Medical Center Phoenix, Arizona
Division of Child Neurology Children's Health Center and Barrow Neurological Institute St. Joseph's Hospital and Medical Center Phoenix, Arizona Hypomagnesemia has previously been recognized as an uncommon cause of seizures. The electrolyte abnormality is caused by poor gastrointestinal absorption or excessive renal wasting, both from a variety of causes. We report on a 5-week-old patient who developed hypomagnesemic seizures as a consequence of renal magnesium wasting. Although the exact pathophysiology of hypomagnesemic seizures remains uncertain, currently available information suggests that it is related to disinhibition of the N-methyl-D-aspartate-type glutamate receptor-sodium channel complex. (J Child Neurol 2002;17:59-61).
Journal of Child Neurology, Vol. 17, No. 1,
59-61 (2002) |
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