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Journal of Child Neurology
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Delayed Onset of Status Epilepticus After Transient Asphyxia in an Asymptomatic Full-Term Neonate

Mark S. Scher, MD

Department of Pediatrics Division of Pediatric Neurology Rainbow Babies and Children's Hospital Cleveland, Ohio, mss20{at}po.cwru.edu

Raymond W. Redline, MD

Department of Pathology University Hospitals of Cleveland and Case Western Reserve University

Barbara A. Bangert, MD

Department of Radiology University Hospitals of Cleveland and Case Western Reserve University Cleveland, Ohio

A full-term neonate presented with status epilepticus at 12 hours of age after a symptom-free interval following transient asphyxia at birth. Conventional neuroimaging failed to detect structural correlates to support recent injury. However, diffusion-weighted magnetic resonance imaging studies revealed recent ischemic brain injury. Placental examination documented multiple subacute and chronic findings indicative of decreased maternal/fetal perfusion. These antepartum placental abnormalities may have been associated with this child's inability to withstand the stress of a prolonged second stage of labor, resulting in intrapartum asphyxia leading to brain injury. This child's clinical presentation highlights the delayed reperfusion phase after ischemia-induced brain injury. (J Child Neurol 2002; 17:780—783).

Journal of Child Neurology, Vol. 17, No. 10, 780-783 (2002)
DOI: 10.1177/08830738020170101806
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