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Journal of Child Neurology
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Height Distribution in Children With Tourette Syndrome

Nathanel Zelnik, MD

Department of Pediatrics, Carmel Medical Center and The B. Rappaport Faculty of Medicine, Technion, Haifa, Israel

Ron S. Newfield, MD

Department of Pediatrics, Carmel Medical Center and The B. Rappaport Faculty of Medicine, Technion, Haifa, Israel

Zmira Silman-Stolar, MSc

Department of Epidemiology, Carmel Medical Center and The B. Rappaport Faculty of Medicine, Technion, Haifa, Israel

Igor Goikhman, MD

Department of Pediatrics, Carmel Medical Center and The B. Rappaport Faculty of Medicine, Technion, Haifa, Israel

Tourette syndrome is characterized by motor and vocal tics, frequently accompanied by attention-deficit hyperactivity disorder (ADHD), obsessive-compulsive disorder, coprolalia, aggressive or self-injurious behavior, and learning disabilities. We investigated the height distribution and clinical characteristics of 38 consecutive patients with Tourette syndrome. Seventeen patients with Tourette syndrome (44.7%) were in the lower height quartile versus 25% from a control group of 44 patients with ADHD (P < .05). The mean standard deviation score differential (patient height - [target height]) was -1.12 ± 0.82 for patients in the first quartile (group A) compared with 0.42 ± 0.63 in taller patients with Tourette syndrome (group B) (P <. .001). The mean birthweight of boys in group A versus group B was 3023 ± 351 g and 3363 ± 486 g, respectively (P < .02); birthweight correlated with standard deviation score (r=.43) . Current weight relative to height was normal. Conduct disorder and/or self-injurious behavior were more common in group A patients (P < .05). Relative short stature appears common in Tourette syndrome, and its presence with other features may implicate a neurotransmitter system that interacts with neuroendocrine pathways, controlling height. (J Child Neurol 2002;17:200-204).

Journal of Child Neurology, Vol. 17, No. 3, 200-204 (2002)
DOI: 10.1177/088307380201700309
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