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Cerebellar Infarction: An Unrecognized Complication of Very Low Birthweight

Department of Pediatrics Section of Pediatric Neurology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, sdjohnse{at}texaschildrenshospital.org

Theodore J. Tarby, MD, PhD

Department of Neurology Section of Pediatric Neurology

Kara Stuart Lewis, MD

Department of Pediatrics Section of Pediatric Neurology, University of Arizona College of Medicine, Tucson, AZ

Roger Bird, MD

Department of Neuroradiology Barrow Neurological Institute, Phoenix, AZ

Erin Prenger, DO

Department of Neuroradiology Barrow Neurological Institute, Phoenix, AZ

We evaluated 13 children with cerebral palsy who had birthweights under 1085 g. A magnetic resonance image (MRI) of the head was obtained, the findings were compared, and the neonatal records were reviewed. The individual children were classified as to the type of cerebral palsy. On MRI, all had severe injury to the inferior cerebellar hemispheres, mostly symmetric, and in some there was injury to the inferior vermis. The average birthweight was 668 g, and the gestational ages were 24 to 27 weeks. No other outstanding prenatal or postnatal problems were identified. The children had different types of severe cerebral palsy, with only 3 being able to walk. Almost all were mentally retarded and microcephalic. All had visual problems. This report defines a previously underappreciated injury to the cerebellum in extremely premature infants. Further clinical, laboratory, and pathologic studies are needed to better defme the underlying mechanisms. (J Child Neurol 2002;17:320-324).

Journal of Child Neurology, Vol. 17, No. 5, 320-324 (2002)
DOI: 10.1177/088307380201700502


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