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Journal of Child Neurology
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Neonatal Mydriasis: Intravenous Lidocaine Adverse Reaction

Itai Berger

Neuro-Pediatric Unit, itberg{at}szmc.org.il

Avraham Steinberg

Neuro-Pediatric Unit

Yechtiel Schlesinger

Infectious Disease Unit

Mordechai Seelenfreund

Department of Ophthalmology

Michael S. Schimmel

Department of Neonatology Shaare Zedek Medical Center Jerusalem, Israel

Lidocaine (a sodium channel blocker) serves as an antiepilepsy drug in neonates. We present a neonate with a seizure disorder who acutely developed pupillary mydriasis secondary to lidocaine overdose. We suggest adding this side effect to the list of untoward effects of lidocaine and to the differential diagnosis of fixed dilated pupils in neonates treated with lidocaine. (J Child Neurol 2002; 17:400-401).

Journal of Child Neurology, Vol. 17, No. 5, 400-401 (2002)
DOI: 10.1177/088307380201700520


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NeoReviewsHome page
C. M.A. Rademaker and L. S. de Vries
Pharmacology Review: Lidocaine for Neonatal Seizure Management
NeoReviews, December 1, 2008; 9(12): e585 - e589.
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