This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Bonkowsky, J. L. Articles by Pavia, A. T. Search for Related Content PubMed PubMed Citation Articles by Bonkowsky, J. L. Articles by Pavia, A. T. Social Bookmarking                         What's this?

Cerebral Aneurysms in a Child With Acquired Immune Deficiency Syndrome During Rapid Immune Reconstitution

Department of Pediatrics University of Utah

John C. Christenson, MD

Department of Pediatrics Division of Infectious Diseases and Geographic Medicine University of Utah

G. William Nixon, MD

Department of Pediatrics University of Utah Division of Pediatric Radiology Primary Children's Medical Center

Andrew T. Pavia, MD

Department of Pediatrics Division of Infectious Diseases and Geographic Medicine University of Utah

A 12-year-old boy with perinatally acquired human immunodeficiency virus infection and Centers for Disease Control and Prevention class C3 disease presented with acute onset of confusion and a right-sided movement disorder 5 months after beginning a new antiretroviral regimen. His CD4 count had been below 50 cells/µL for 4 years but had abruptly risen to more than 250 cells/µL. Computed tomographic and magnetic resonance imaging scans showed cerebral aneurysms and new cerebral lesions consistent with ischemic strokes. The presentation during immune reconstitution suggests that cerebral aneurysms in pediatric patients with acquired immune deficiency syndrome can result from an immune-mediated response to chronic vascular infection. (J Child Neurol 2002;17:457-460).

Journal of Child Neurology, Vol. 17, No. 6, 457-460 (2002)
DOI: 10.1177/088307380201700613


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				D. A. GOLDSTEIN, J. TIMPONE, and T. R. CUPPS HIV-associated Intracranial Aneurysmal Vasculopathy in Adults J Rheumatol, February 1, 2010; 37(2): 226 - 233. [Abstract] [Full Text] [PDF]

				N J Cutfield, H Steele, T Wilhelm, and M W Weatherall Successful treatment of HIV associated cerebral vasculopathy with HAART J. Neurol. Neurosurg. Psychiatry, August 1, 2009; 80(8): 936 - 937. [Full Text] [PDF]

				J. Bonkowsky, A. Pavia, M. Zuber, E. Touze, and M. Kossorotoff Cerebral vasculopathy with aneurysm formation in HIV-infected young adults Neurology, February 20, 2007; 68(8): 623 - 623. [Full Text] [PDF]

				B. Tipping, L. de Villiers, S. Candy, and H. Wainwright Stroke Caused by Human Immunodeficiency Virus-Associated Intracranial Large-Vessel Aneurysmal Vasculopathy Arch Neurol, November 1, 2006; 63(11): 1640 - 1642. [Abstract] [Full Text] [PDF]