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Journal of Child Neurology
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Spontaneous Long-Term Remission of Intractable Partial Epilepsy in Childhood

Pratima Pandley

Department of Transitional Medicine

Jagdish Shah

Department of Neurology

Csaba Juhász

Department of Pediatrics

Zoltán Pfund

Department of Pediatrics

Harry T. Chugani

Departments of Neurology, Pediatrics, and Radiology Children's Hospital of Michigan/Detroit Medical Center Wayne State University School of Medicine Detroit, Michigan

Drug-resistant partial epilepsy in children often has a major impact on cognitive development, and early surgical intervention has been advocated to prevent adverse neurobehavioral effects of seizures in such patients. We report a 5-year-old boy who had cryptogenic partial epilepsy of right parietal origin as documented by ictal electroencephalogram (EEG) and glucose metabolism positron emission tomographic (PET) scan. His atonic seizures could not be controlled by multiple antiepilepsy drugs; therefore, cortical resection was scheduled. However, his seizures remitted spontaneously after 1 year of failed medical treatment. The epileptiform abnormality disappeared on the follow-up EEGs, and a glucose PET scan also normalized. This boy has fully retained his cognitive and motor functions and has remained seizure free in the past 4z\x years off medications. (J Child Neurol 2002;17:466-470).

Journal of Child Neurology, Vol. 17, No. 6, 466-470 (2002)
DOI: 10.1177/088307380201700616
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