Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

http://mc.manuscriptcentral.com/childneurology

Click here to sign up for SAGE Journal Email Alerts today!
Journal of Child Neurology
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Parmeggiani, A.
Right arrow Articles by Giovanardi-Rossi, P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Parmeggiani, A.
Right arrow Articles by Giovanardi-Rossi, P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

Epilepsy, Intelligence, and Psychiatric Disorders in Patients With Cerebellar Hypoplasia

Antonia Parmeggiani, MD

Child Neurology and Psychiatry Unit, Department of Neurological Sciences, University of Bologna, Italy, parmeggi{at}alma.unibo.it

Annio Posar, MD

Child Neurology and Psychiatry Unit, Department of Neurological Sciences, University of Bologna, Italy

Maria Cristina Scaduto, MD

Child Neurology and Psychiatry Unit, Department of Neurological Sciences, University of Bologna, Italy

Simona Chiodo, MD

Child Neurology and Psychiatry Unit, Department of Neurological Sciences, University of Bologna, Italy

Paola Giovanardi-Rossi, MD

Child Neurology and Psychiatry Unit, Department of Neurological Sciences, University of Bologna, Italy

The cerebellum is involved in motor and cognitive functions and behavior. Its role in controlling epileptic seizures has been demonstrated in the literature. Genetic factors can enhance epilepsy susceptibility when the cerebellum is damaged. We examined the occurrence and features of epilepsy, intelligence, and psychiatric disorders in 28 patients with cerebellar hypoplasia. We compared patients with (10; 35.7%) and without (18; 64.3%) epilepsy. The statistical evaluation showed a significant prevalence of familial antecedents for seizures in patients with epilepsy (P < .01); cerebral associated lesions and type of cerebellar hypoplasia did not influence the occurrence of epilepsy, which was partial in 80% of cases. Profound mental retardation prevailed in patients with epilepsy (P < .05). Both mental retardation (75%) and pervasive developmental disorders (17.8%) prevailed in our cases with respect to the general population (P < .000). Cerebellar hypoplasia in our sample seems to be an important risk factor for the occurrence of epilepsy, mental retardation, and psychiatric disorders. (J Child Neurol 2003; 18: 1—4).

Journal of Child Neurology, Vol. 18, No. 1, 1-4 (2003)
DOI: 10.1177/08830738030180011001
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?


This article has been cited by other articles:


Home page
 J Child NeurolHome page
A. Parmeggiani, A. Posar, and M. C. Scaduto
Cerebellar Hypoplasia, Continuous Spike-waves During Sleep, and Neuropsychological and Behavioral Disorders
J Child Neurol, December 1, 2008; 23(12): 1472 - 1476.
[Abstract] [PDF]

Home page
 J Child NeurolHome page
P. Ventura, A. Presicci, T. Perniola, M. G. Campa, and L. Margari
Mental Retardation and Epilepsy in Patients With Isolated Cerebellar Hypoplasia
J Child Neurol, September 1, 2006; 21(9): 776 - 781.
[Abstract] [PDF]