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Journal of Child Neurology, Vol. 18, No. 1, 64-67 (2003)
DOI: 10.1177/08830738030180011501

Atypical Features of Medulloblastoma on Magnetic Resonance Imaging

Case Report and Review of the Literature

Robert Lopez-Alberola

Departments of Psychiatry and Neurology Tulane University School of Medicine dlee{at}tulane.edu

Meena Bhattacharjee

Department of Pathology Tulane University School of Medicine

Jessica Borne

Department of Radiology Louisiana State University Health Sciences Center

Deborah A. Lee

Departments of Psychiatry and Neurology Tulane University School of Medicine New Orleans, Louisiana

Magnetic resonance imaging (MRI) is the radiologic modality of choice used to evaluate suspected lesions in the posterior fossa, given its greater sensitivity compared with other neuroimaging techniques. The case of a 9-year-old girl with progressive ataxia is presented. MRI of the brain demonstrated nonspecific T 2 -weighted abnormalities involving the cerebellar vermis with minimal mass effect suggested by asymmetric enlargement of the left superior cerebellar peduncle. Postgadolinium studies showed only minimal enhancement of the left superior cerebellar peduncle. After an MRI of the spine demonstrated drop metastases, a cerebellar biopsy was performed, which revealed an infiltrating medulloblastoma confined to the granular layer and leptomeninges. Hence, MRI is an important ancillary tool in the diagnosis of medulloblastoma, but caution needs to be taken when interpreting imaging studies. (J Child Neurol 2003; 18: 64—67).


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