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Journal of Child Neurology
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Opsoclonus: An Early Sign of Neonatal Herpes Encephalitis

Stanley Krolczyk, MD

Department of Neurology Cleveland Clinic Weston, Florida

Esperanza Pacheco, MD

Department of Radiology Miami Children's Hospital

Pablo Valencia, MD

Division of Neonatology Department of Pediatrics Miami Children's Hospital

Oscar Papazian, MD

Division of Neurophysiology Department of Neurology Miami Children's Hospital Miami, Florida

Karina Yelin, MD

Division of Neonatal Neurology Department of Neurology Miami Children's Hospital and University of Miami Miami, Florida

Israel Alfonso, MD

Division of Neonatal Neurology Department of Neurology Miami Children's Hospital and University of Miami Miami, Florida, dr.alfonso{at}mindspring.com.

Preferential involvement of certain central nervous systems areas by specific viruses provides a valuable guide to the selection of antiviral agents. We report a neonate that developed opsoclonus 7 days prior to the diagnosis of herpes simplex type 2 cerebellitis. The course of the opsoclonus paralleled the clinical course and radiologic evolution of the infection. The purpose of this report is to describe opsoclonus as a possible early sign of herpes simplex type 2 central nervous system infection. (J Child Neurol 2003;18:356—358).

Journal of Child Neurology, Vol. 18, No. 5, 356-358 (2003)
DOI: 10.1177/08830738030180050201
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