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Juvenile-Onset Leigh Syndrome With an Acute Polyneuropathy at Presentation

Department of Neurology,University of Florida Gainesville, Florida

Paul R. Carney, MD

Department of Pediatrics,University of Florida Gainesville, Florida

Edward R. Valenstein, MD

Department of Neurology University of Florida Gainesville, Florida

Subacute necrotizing encephalomyelopathy or Leigh syndrome can be associated with a polyneuropathy. By far, the most commonly encountered neuropathy is a chronic neuropathy with features of demyelination, which can be the presenting manifestation of Leigh syndrome. On rare occasions, the neuropathy encountered can represent a more acute process. We describe a rare case of juvenile-onset Leigh syndrome presenting with an acute polyneuropathy. (J Child Neurol 2003;18:574—576).

Journal of Child Neurology, Vol. 18, No. 8, 574-576 (2003)
DOI: 10.1177/08830738030180081101


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