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Progressive Multifocal Leukoencephalopathy Successfully Treated With Highly Active Antiretroviral Therapy and Cidofovir in an Adolescent Infected With Perinatal Human Immunodeficiency Virus (HIV)

Department of Pediatrics College of Physicians and Surgeons Columbia University New York, New York Harlem Hospital Center, New York, New York, lr2043{at}columbia.edu.

Claudia A. Chiriboga, MD, MPH

Harlem Hospital Center New York, New York Division of Pediatric Neurology, Department of Neurology College of Physicians and Surgeons, Columbia University, New York, New York

Susan E. Champion, MD, MPH

Department of Pediatrics College of Physicians and Surgeons Columbia University New York, New York Harlem Hospital Center, New York, New York

Ivan Ainyette, PhD

Harlem Hospital Center New York, New York Department of Psychiatry College of Physicians and Surgeons, Columbia University, New York, New York Monica DiGrado, RNC

Elaine J. Abrams, MD

Department of Pediatrics College of Physicians and Surgeons, Columbia University New York, New York Harlem Hospital Center, New York, New York

Progressive multifocal leukoencephalopathy is an infectious demyelinating brain disease caused by the JC virus that is associated with significant morbidity and mortality in the immunocompromised host. We report a case of progressive multifocal leukoencephalopathy successfully treated with highly active antiretroviral therapy and cidofovir in an adolescent patient perinatally infected with human immunodeficiency virus (HIV). ( J Child Neurol 2004;19:35—38).

Journal of Child Neurology, Vol. 19, No. 1, 35-38 (2004)
DOI: 10.1177/088307380401900107011


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