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Journal of Child Neurology
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Norepinephrine and Dopamine Metabolites and Educational Variables in Boys With Attention Deficit Disorder and Hyperactivity

Walid O. Shekim, MD

UCLA Child Psychiatry and Mental Retardation program, Los Angeles

Esther Sinclair, PhD

UCLA Child Psychiatry and Mental Retardation program, Los Angeles

Robert Glaser, MA

MidMissouri Mental Health Center and Department of Psychiatry

Ellen Horwitz, MA

MidMissouri Mental Health Center and Department of Psychiatry

Javaid Javaid, PhD

the Illinois State Psychiatry Institute, Chicago

David B. Bylund, PhD

Department of Pharmacology University of Missouri-Columbia School of Medicine, Columbia, MO

The present study evaluated the biochemical measures of urinary homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) in relation to functioning on selected psychoeducational tests in a group of boys with attention deficit disorder and hyperactivity. The Wechsler Intelligence Scale for Children-Revised (WISC-R), the Wide Range Achievement Test (WRAT), and the Peabody Picture Vocabulary Test were administered to 28 hyperactive and 23 control subjects. The findings suggest subtle differences in psychoeducational test performance in relation to specific levels of homovanillic acid and MHPG. (J Child Neurol 1987;2:50-56).

Journal of Child Neurology, Vol. 2, No. 1, 50-56 (1987)
DOI: 10.1177/088307388700200110
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[Abstract] [PDF]