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Journal of Child Neurology
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Reviews

Review Article: Understanding and Preventing Perinatal, Intracerebral, Peri- and Intraventricular Hemorrhage

Jan Goddard-Finegold, MD

Departments of Pediatrics and Pathology, Baylor College of Medicine, Neurology Service Texas Children's Hospital, Houston, TX

Eli M. Mizrahi, MD

Departments of Neurology and Neurophysiology, Baylor College of Medicine, Neurology Service, Texas Children's Hospital, Houston, TX

Antenatal anticipation of problem pregnancies and improvements in resuscitation and care of newborns have led to increasing survival of babies born prematurely. Nevertheless, the potential for neurologic handicaps is significant in this population of children, and the prevention of intracerebral, peri- and intraventricular hemorrhages and associated brain lesions remains a high priority. In this review, we consider (1) the clinical problem of periventricular, intraventricular hemorrhage; (2) means of diagnosis; (3) the EEG and periventricular, intraventricular hemorrhage; (4) sequelae; (5) hypotheses of pathogenesis; (6) experimental approaches to understanding periventricular, intraventricular hemorrhage; (7) agents being tested for use in preventing hemorrhage; and (8) future areas for research toward the prevention of hemorrhage and other neonatal brain lesions. (J Child Neurol 1987;2:170-185).

Journal of Child Neurology, Vol. 2, No. 3, 170-185 (1987)
DOI: 10.1177/088307388700200302
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This article has been cited by other articles:


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L. M. Ford, J. Steichen, P. A. Steichen Asch, D. Babcock, and M. H. Fogelson
Neurologic Status and Intracranial Hemorrhage in Very-Low-Birth-Weight Preterm Infants: Outcome at 1 Year and 5 Years
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[Abstract] [PDF]

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 CLIN PEDIATRHome page
L. M. Ford, B. Kim Han, J. Steichen, D. Babcock, and H. Fogelson
Very-low-birth-weight, Preterm Infants With or Without Intracranial Hemorrhage: Neurologic, Cognitive and Cranial MRI Correlations at 4-8-year Follow-up
Clinical Pediatrics, July 1, 1989; 28(7): 302 - 310.
[Abstract] [PDF]