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Journal of Child Neurology
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Depressed Left Ventricular Contractile Reserve Diagnosed by Dobutamine Stress Echocardiography in a Patient With Duchenne Muscular Dystrophy

Brenda L. Y. Wong, MBBS, MRCP (UK)

Division of Child Neurology Cincinnati Children's Hospital Medical Center Cincinnati, Ohio, brenda.wong{at}cchmc.org

Vincent A. Mukkada, MD

Department of Pediatrics Brown University Hasbro Children's Hospital Providence, Rhode Island

Larry W. Markham, MD

Division of Pediatric Cardiology Cincinnati Children's Hospital Medical Center Cincinnati, Ohio

Linda H. Cripe, MD

Division of Pediatric Cardiology Cincinnati Children's Hospital Medical Center Cincinnati, Ohio

Cardiomyopathy is a leading cause of death in patients with Duchenne muscular dystrophy. Congestive heart failure is often subclinical and unrecognized as a result of the severe physical limitations of this patient population. We report the case of a 16-year-old boy with Duchenne muscular dystrophy who demonstrated normal left ventricular systolic function at rest by screening transthoracic echocardiogram. This patient, however, was noted to have depressed left ventricular contractile reserve by dobutamine stress echocardiography. Dobutamine stress echocardiography can have an important role in unmasking subclinical heart failure in this patient population. (J Child Neurol 2005;20:246—248).

Journal of Child Neurology, Vol. 20, No. 3, 246-248 (2005)
DOI: 10.1177/08830738050200031401
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