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Journal of Child Neurology
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*Cytomegalovirus Infections
*Developmental Disabilities
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Not a New Leukodystrophy but Congenital Cytomegalovirus Infection

Burak Tatli, MD

Division of Child Neurology Department of Pediatrics Istanbul Medical Faculty Istanbul University Istanbul, Turkey, buraktat{at}yahoo.com

Meral Ozmen, MD

Division of Child Neurology Department of Pediatrics Istanbul Medical Faculty Istanbul University Istanbul, Turkey

Nur Aydinli, MD

Division of Child Neurology Department of Pediatrics Istanbul Medical Faculty Istanbul University Istanbul, Turkey

Mine Caliskan, MD

Division of Child Neurology Department of Pediatrics Istanbul Medical Faculty Istanbul University Istanbul, Turkey

Pauline M. Wertheim-van Dillen, MD, PhD

Department of Medical Microbiology Laboratory for Clinical Virology Academic Medical Center Amsterdam, The Netherlands

Marjo S. van der Knaap, MD, PhD

Department of Child Neurology Vrije Universiteit Medical Center Amsterdam, The Netherlands

We report a 16-month-old girl who presented with global developmental delay and hearing loss. Cranial magnetic resonance imaging demonstrated a pattern that could be interpreted as a "new leukoencephalopathy." Etiologic investigations revealed a positive polymerase chain reaction for cytomegalovirus DNA using her stored Guthrie card, indicating a congenital cytomegalovirus infection. (J Child Neurol 2005;20:525—527).

Journal of Child Neurology, Vol. 20, No. 6, 525-527 (2005)
DOI: 10.1177/08830738050200061101
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