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Multivoxel Magnetic Resonance Spectroscopy in a Rhizomelic Chondrodysplasia Punctata Case

Ahmet Siirci, MD

Department of Radiology, Inonu University School of Medicine Malatya, Turkey, ahmets{at}inonu.edu.tr.

Alpay Alkan, MD

Department of Radiology, Inonu University School of Medicine Malatya, Turkey

Ramazan Kutlu, MD

Department of Radiology, Inonu University School of Medicine Malatya, Turkey

Hande Gülcan, MD

Department of Radiology, Inonu University School of Medicine Malatya, Turkey

A case of a 5-day-old newborn with rhizomelic chondrodysplasia punctata was investigated with multivoxel magnetic resonance spectroscopy, including chemical shift imaging maps, which disclosed a decrease in the choline peak and the choline signal intensity, respectively, in the right cerebral hemisphere. This is the second report of multivoxel magnetic resonance spectroscopy examination of the brain associated with rhizomelic chondrodysplasia punctata in the literature. Multivoxel magnetic resonance spectroscopy with chemical shift imaging maps has the advantage of obtaining more information in a short period of time, which shortens the duration of anesthesia and its associated risks and complications. We suggest that future efforts be directed to evaluating such patients with multivoxel magnetic resonance spectroscopy instead of single-voxel magnetic resonance spectroscopy. (J Child Neurol 2005;20:698—701).

Journal of Child Neurology, Vol. 20, No. 8, 698-701 (2005)
DOI: 10.1177/08830738050200081401


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