This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Needelman, H. Articles by Schaefer, B. Search for Related Content PubMed PubMed Citation Articles by Needelman, H. Articles by Schaefer, B. Social Bookmarking                   What's this?

Ontogeny and Physiology of the Cavum Septum Pellucidum in Premature Infants

Munroe-Meyer Institute for Genetics and Rehabilitation University of Nebraska Medical Center, Omaha, NE

Bruce Schroeder, MD

Department of Radiology Children's Memorial Hospital, Omaha, NE

Matthew Sweney, MD

Department of Pediatrics University of Nebraska Medical Center, Omaha, NE

John Schmidt, MD

Department of Pediatrics University of Nebraska Medical Center, Omaha, NE

John B. Bodensteiner, MD

Section of Pediatric Neurology Barrow Neurological Institute, St. Joseph's Hospital, Phoenix, AZ

Bradley Schaefer, MD

Munroe-Meyer Institute for Genetics and Rehabilitation University of Nebraska Medical Center, Omaha, NE

We report the natural history of the closure of the cavum septum pellucidum in 47 premature infants. In this study, a cavum septum pellucidum was present in all patients at 25 to 26 weeks' postconceptual age, in keeping with previous reports. The data from this study suggest that premature delivery does not change the natural history of the normal closure of the cavum septum pellucidum in most infants by 36 to 40 weeks' postconceptual age. Although not statistically significant, there is a suggestion from these data that higher grades of intraventricular hemorrhage are more frequently associated with loss (early closure) of the cavum septum pellucidum. One particularly illustrative case with a grade 4 intraventricular hemorrhage and subsequent hydrocephalus suggests that increases in pressure and volume in the lateral ventricles can cause the laminae of the septum pellucidum to approximate and appear to fuse earlier than expected. However, the fact that the cavum septum pellucidum reappeared in this case after ventricular pressure was decreased (postventricular shunt) suggests that approximation is not the sole factor in definitive fusion of the laminae of the septum pellucidum. (J Child Neurol 2006;21:298—300; DOI 10.2310/7010.2006.00081).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				D. L. Montgomery, A. Van Olphen, H. Van Campen, and T. R. Hansen The Fetal Brain in Bovine Viral Diarrhea Virus-infected Calves: Lesions, Distribution, and Cellular Heterogeneity of Viral Antigen at 190 Days Gestation Vet. Pathol., May 1, 2008; 45(3): 288 - 296. [Abstract] [Full Text] [PDF]

				H. Needelman, B. Schroeder, M. Sweeney, J. Schmidt, J. B. Bodensteiner, and G.B. Schaefer Postterm Closure of the Cavum Septi Pellucidi and Developmental Outcome in Premature Infants J Child Neurol, March 1, 2007; 22(3): 314 - 316. [Abstract] [PDF]