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Electroencephalographic (EEG) Findings in Posterior Reversible Encephalopathy Associated With Immunosuppressants

Department of Pediatrics Nagoya University Graduate School of Medicine Nagoya, Japan, junnatsu{at}med.nagoya-u.ac.jp

Ayako Sofue, MD, PhD

Department of Pediatrics Japanese Red Cross Nagoya First Hospital Nagoya, Japan

Akio Yamada, MD

Department of Pediatrics Social Insurance Chukyo Hospital Nagoya, Japan, Department of Pediatrics Japanese Red Cross Nagoya First Hospital Nagoya, Japan

Koji Kato, MD

Department of Pediatrics Social Insurance Chukyo Hospital Nagoya, Japan, Department of Pediatrics Japanese Red Cross Nagoya First Hospital Nagoya, Japan

Posterior reversible encephalopathy has been reported in patients who receive immunosuppressants. Compared with radiologic studies, electroencephalographic (EEG) findings are not well described. We performed EEG serially in three children who suffered from posterior reversible encephalopathy associated with tacrolimus or cyclosporine. EEG showed continuous focal rhythmic activities in the acute period. EEG findings normalized after the clinical manifestations had disappeared. We conclude that EEG is useful for the diagnosis and follow-up of posterior reversible encephalopathy. (J Child Neurol 2006;21: 620—623; DOI 10.2310/7010.2006.00147).

Journal of Child Neurology, Vol. 21, No. 7, 620-623 (2006)
DOI: 10.1177/08830738060210071201


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