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Journal of Child Neurology
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Intra-arterial Thrombolysis in a 2-Year-Old with Cardioembolic Stroke

Susan L. Benedict, MD

Departments of Pediatrics and Neurology, University of Utah, and Primary Children's Medical Center, Salt Lake City, Utah, susan.benedict{at}hsc.utah.edu

Oliver K. Ni, MD

Department of Neurology, University of Utah, Salt Lake City, Utah

Peter Schloesser, MD

Department of Radiology, University of Utah, and Primary Children's Medical Center, Salt Lake City, Utah

Keith S. White, MD

Department of Radiology, University of Utah, and Primary Children's Medical Center, Salt Lake City, Utah

James F. Bale, Jr, MD

Departments of Pediatrics and Neurology, University of Utah, and Primary Children's Medical Center, Salt Lake City, Utah

Recombinant tissue plasminogen activator, although the standard of care for the management of acute ischemic stroke in adults, is used infrequently in children. The authors describe the use of intra-arterial recombinant tissue plasminogen activator in a young child with embolic stroke. Thrombolysis restored flow to the affected middle cerebral artery and appeared to limit the extent of the infarction and the severity of the subsequent neurologic deficits.

Key Words: stroke • thrombolysis • recombinant tissue plasminogen activator

Journal of Child Neurology, Vol. 22, No. 2, 225-227 (2007)
DOI: 10.1177/0883073807300296
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