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Journal of Child Neurology
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Neurodevelopment in Very Low Birth Weight Premature Infants With Postnatal Subependymal Cysts

Yao-Chia Chuang, MD

Department of Physical Medicine and Rehabilitation, Mackay Memorial Hospital, Taipei, Taiwan, pmrchia{at}yahoo.com, Mackay Medicine, Nursing and Management College, Taipei, Taiwan

Chia Lee, MD

Department of Physical Medicine and Rehabilitation, Mackay Memorial Hospital, Taipei, Taiwan

Nan-Chang Chiu, MD

Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan

Chyong-Hsin Shu, MD

Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan

Han-Yang Hung, MD

Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan

Hsin-An Kao, MD

Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan

Jui-Hsing Chang, MD

The aim of this study was to investigate the neurodevelopmental outcome in very low birth weight infants with postnatal subependymal cysts. During a 3-year period, postnatal subependymal cysts were diagnosed by serial cranial ultrasound in 21 very low birth weight infants born prior to 33 weeks' gestation. These infants and 116 healthy very low birth weight controls were evaluated with the Bayley Scales of Infant Development at 2 years of age. Preterm infants with postnatal subependymal cysts had a significantly lower Psychomotor Development Index (P = .034) and were more likely than the normal group to have motor developmental delay (Psychomotor Development Index <70) (P = .013). The findings indicate that postnatal subependymal cyst is a significant risk factor for impaired motor development in very low birth weight infants (odds ratio 5.73, 95% confidence interval 1.57—20.97).

Key Words: subependymal cyst • low birth weight

Journal of Child Neurology, Vol. 22, No. 4, 402-405 (2007)
DOI: 10.1177/0883073807301924
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This article has been cited by other articles:


Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
J R Fernandez Alvarez, P N Amess, R S Gandhi, and H Rabe
Diagnostic value of subependymal pseudocysts and choroid plexus cysts on neonatal cerebral ultrasound: a meta-analysis
Arch. Dis. Child. Fetal Neonatal Ed., November 1, 2009; 94(6): F443 - F446.
[Abstract] [Full Text] [PDF]