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Journal of Child Neurology, Vol. 22, No. 9, 1121-1123 (2007)
DOI: 10.1177/0883073807306266
© 2007 SAGE Publications

Autistic Disorder in 2 Children With Mitochondrial Disorders

Chang-Yong Tsao, MD

Departments of Pediatrics and Neurology, The Ohio State University, Columbus, Ohio, tsaoc{at}pediatrics.ohio-state.edu

Jerry R. Mendell, MD

Departments of Pediatrics and Neurology, The Ohio State University, Columbus, Ohio

Autistic disorder is a heterogeneous disorder. The majority of the cases are idiopathic, and only a small number of the autistic children have associated secondary diagnosis. This article reports 2 children with mitochondrial disorders associated with autistic disorder fulfilling the diagnostic criteria of the American Psychiatric Association Manual of Psychiatric Diseases, 4th edition, and briefly reviews the literature on autistic disorder associated with mitochondrial disorders.

Key Words: mitochondrial • autism


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