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Journal of Child Neurology, Vol. 22, No. 9, 1132-1134 (2007)
DOI: 10.1177/0883073807306252
© 2007 SAGE Publications

Splenial Corpus Callosum Lesion and Hemifield Visual Color Anomia Associated With Intracranial Hypertension

Joshua L. Bonkowsky, MD, PhD

Division of Pediatric Neurology and Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah, joshua.bonkowsky{at}hsc.utah.edu

Francis M. Filloux, MD

Division of Pediatric Neurology and Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah

Judith E. Warner, MD

Department of Neurology University of Utah School of Medicine, Salt Lake City, Utah

Lesions in the splenium of the corpus callosum are a rare complication of a variety of clinical conditions including ischemia, trauma, acute disseminated encephalomyelitis, infection, electrolyte imbalances, seizures, and antiepileptic drugs. This report describes a child presenting with hemifield visual color anomia, headache, and papilledema, who was found to have a midline splenial lesion on diffusion-weighted magnetic resonance imaging (MRI). Lumbar puncture revealed elevated intracranial pressure. His symptoms and MRI findings resolved quickly following treatment of his increased intracranial pressure. This is the first report describing an association between intracranial hypertension and a lesion in the splenium of the corpus callosum.

Key Words: corpus callosum • splenium • intracranial hypertension • hypothyroidism • magnetic resonance imaging (MRI) • disconnection syndrome • hemifield visual color anomia


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