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Journal of Child Neurology
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The Successful Use of Ondansetron in a Boy With Both Leukemia and Tourette Syndrome

Renata Rizzo, MD, PhD

Section of Child Neuropsychiatry, Department of Pediatrics University of Catania, Azienda Policlinico, Catania, Italy, rerizzo{at}unict.it

Santo Marino, MD

Section of Child Onco-hematology, Department of Pediatrics University of Catania, Azienda Policlinico, Catania, Italy

Mariangela Gulisano, MD

Section of Child Neuropsychiatry, Department of Pediatrics University of Catania, Azienda Policlinico, Catania, Italy

Mary M. Robertson, MD, FRCP, FRCPCH, FRCPsych, DSc (Med)

University College, London, UK

This article reports an 8-year-old boy with both acute lymphoblastic leukemia and Gilles de la Tourette syndrome. Initially, for his leukemia, he was treated with chemotherapy, which resulted in severe nausea and vomiting for which he was given ondansetron. This not only relieved the target symptoms, but also those of his Gilles de la Tourette syndrome. Following a reduction of the ondansetron dosage, his Gilles de la Tourette syndrome symptoms reemerged.

Key Words: ondansetron • Tourette • leukemia

Journal of Child Neurology, Vol. 23, No. 1, 108-111 (2008)
DOI: 10.1177/0883073807307085
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