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Neurologic Sequelae of Neonatal Hypoglycemia in Kayseri, Turkey

Paediatric Neurology, Department of Pediatrics, Erciyes University Faculty of Medicine, Kayseri, Turkey, huseyinper{at}yahoo.com

Sefer Kumanda, MD

Paediatric Neurology, Department of Pediatrics, Erciyes University Faculty of Medicine, Kayseri, Turkey

Abdulhakim Çoskun, MD

Paediatric Radiology, Department of Radiology, Erciyes University Faculty of Medicine, Kayseri, Turkey

Hakan Gümü, MD

Paediatric Neurology, Department of Pediatrics, Erciyes University Faculty of Medicine, Kayseri, Turkey

Didem Öztop, MD

Child Psychiatry, Department of Child Psychiatry, Erciyes University Faculty of Medicine, Kayseri, Turkey

Contrary to belief, neonatal hypoglycemia is relatively common and can cause more severe neurological sequelae than is currently believed. Prevention of hypoglycemic brain damage by hindering prolonged and profound neonatal hypoglycemia might contribute to psychomotor development. At Erciyes University, between December 1996 and 2005, of the patients who applied to Paediatric Neurology Department, 60 cases with a history of neonatal hypoglycemia were included in the study. The magnetic resonance imaging (MRI) scans and clinical records of all patients were reviewed retrospectively. It was noted that the sequelae with glucose levels of 0 0 to 40 were more serious and intense. The same results were also observed in cranial MRI evaluation. In conclusion, intractable epilepsy, mental motor retardation, cerebral palsy, and visual disturbance were found to be the most common and severe conditions affecting sufferers of neonatal hypoglycemia. In the first 3 days of life, the close monitoring of patients at risk is critical, and hospitalization of severe cases should be considered.

Key Words: neonatal hypoglycemia • neurologic sequelae • magnetic resonance findings

Journal of Child Neurology, Vol. 23, No. 12, 1406-1412 (2008)
DOI: 10.1177/0883073808319075


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